A 2003 study found that grape seed extract worked well in replacing estrogen and blunting hypertension in postmenopausal women. More recent research suggests that grape seed extract may work at the genetic level, activating a gene that stops oxidation of bad cholesterol. Further research led to the OPCs concentrated in grape seeds. This was credited to their widespread consumption of red wine. Its antioxidant properties were realized in the 1980s with the socalled French paradox, in which researchers discovered that the French had low rates of heart disease even though their diet was high in cholesterol. Grape seed extract is a relatively new supplement in the United States, although it has been used in Europe for several decades. Tyler, dean emeritus of the Purdue University School of Pharmacy and Pharmacal Sciences, the procyanidin compounds found in grape seed extract are useful in treating vascular disorders They also are antioxidants, or freeradical scavengers, that help prevent some age-related cancers and atherosclerosis. It is available as an over-the-counter supplement. Most of the research on grape seed extract has been done in Europe, so many of its reported benefits have not been reviewed or approved by the U.S. They also are able to cross the stubborn blood-brain barrier, providing antioxidant protection to the brain and nervous system. OPCs in the extract are water-soluble, making them easily absorbed by the body. Procyanidins, a group of compounds found in the extract, are thought to increase the effectiveness of other antioxidants, especially vitamin C and vitamin E, by helping them regenerate after neutralizing free radicals in the blood and tissue. Its antioxidant properties are believed to help slow the aging process. It has a wide range of therapeutic uses, from preventing cancer and cardiovascular disease to alleviating symptoms of allergies, ulcers, and cataracts. Grape seed extract is a mixture of complex compounds. However, the grape seed extract is more widely recommended for its lower cost and because it contains an antioxidant not found in pine bark. The primary sources of OPCs are pine bark extract and grape seed extract. Laboratory studies have indicated OPCs are much more effective than vitamin C and vitamin E in neutralizing free oxygen radicals, which contribute to organ degeneration and aging in humans. MEND Regenerate is the all-in-one, daily nutrition solution to get more grape seed extract and support your everyday health and vitality.Grape seed extract is the primary commercial source of a group of powerful antioxidants known as oligomeric proanthocyanidins (OPCs), also generically called pycnogenol, a class of flavonoids. Alongside grape seed extract, key ingredients include: Vitamins C and D to support bone health protein and amino acids designed to fuel muscle growth and strength creatine and vitamin B complex to enhance energy, vitality, and endurance as well as COQ10, an antioxidant that protects cells from damage and plays an important role in metabolic processes. MEND Regenerate is the only product of its kind that contains grape seed extract and 32 additional nutrients that work together to fuel optimal living and peak health. Grape seed extract is particularly powerful when taken in conjunction with other nutrients, vitamins and antioxidant supplements. Powering your body daily with grape seed extract can boost long-term health and wellness, but it’s not the be-all-end-all for your health. Grape seed extract is commonly available as a dietary supplement in a liquid form, tablets, or capsules. Improved cognition: Grape seed extract has been associated with improvements in reaction time and psychomotor skills among older adults, helping to slow and reduce the cognitive effects of aging.Improved cardiovascular health: The antioxidants found in grape seed extract can help protect blood vessels from becoming damaged, which can lead to higher blood pressure and improve overall cardiac function.Its OPCs help to minimize symptoms of chronic venous insufficiency, blood pools in the legs that cause pain, swelling and visible veins. Reduced inflammation: Swelling caused by surgery or an injury can be reduced more quickly by taking grape seed extract.The powerful antioxidant also enhances the formation of epidermal tissue so it is stronger and healthier after healing, and improves function of connective tissue. The extract increases levels of tenascin, a protein that helps build the connective tissue that appears as pink skin when a wound is healing. Enhanced wound healing: Grape seed extract has been proven to help wounds heal more rapidly and with less scarring. ![]() It’s clear the benefits of grape seed extract are plentiful, but how can you see these health advantages in day-to-day life?
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